This is relatively self explanatory, but I have a few tips to share. When blending thicker mixtures, sometimes enough sticks to the inside of the blender after pouring it out that it seems like a waste to just wash it down the drain. For things like smoothies I like to put in just enough water to reach the blades, briefly spin it up to full speed, and then pour into my glass (after I’ve finished my smoothie). At first this watered-down smoothie may seem weird, but it’s really grown on me, and I think it’s worth it as a fast way to not waste any of a smoothie.
If you are making a nut butter, after scraping it out you can then make a smoothie, and the remaining bits of nut butter will be blended into the smoothie.
For scraping the last bit out a narrow silicone spatula can be helpful. I don’t see the one I have currently available, but this one looks like a good choice. (One-piece spatulas are nice because you don’t have to worry about the end coming off or debris getting trapped in the junction.)
Vitamix also sells a set of nylon spatulas that I am curious about, but have not tried. They might be better than the flexible spatula for very thick mixtures like nut butter. One thing about both these nylon spoons and silicone spatulas is that if you’re not careful the blades can nick them. For that reason a long skinny wooden spoon like this one might be nice for getting in around the blades. Update: I’ve tried out the nylon spatulas and they work well. Update 2: I’ve now used aforementioned skinny silicone spatula, and it works great.
Once I’ve gotten as much out as I want, I usually give the lid and pitcher a few rinses to remove visible debris, then put in a drop of dish soap and a few cups of hot water, and run on high for 10-30 seconds. It’s sometimes tempting to skip the soap because it seems unnecessary, but if you don’t use soap a film will build up on the container. It’s not a big deal, but it’s nice to avoid.
If you made something really thick like nut butter or bread dough you might need to use a non-abrasive sponge to clean stuck bits off the sides. I’ve found that the blades always get themselves clean, so you do not need use a sponge on them. (For oily things like nut butter, sometimes I add a little extra soap and make sure to use hot water.)